Toll-Like Receptor 2 (TLR2) and TLR4 Mediate the IgA Immune Response Induced by Mycoplasma hyopneumoniae
Identifieur interne : 000320 ( Main/Exploration ); précédent : 000319; suivant : 000321Toll-Like Receptor 2 (TLR2) and TLR4 Mediate the IgA Immune Response Induced by Mycoplasma hyopneumoniae
Auteurs : Xia Li [République populaire de Chine] ; Yun-Ke Zhang [République populaire de Chine] ; Bao Yin [République populaire de Chine] ; Jing-Bo Liang [République populaire de Chine] ; Fei Jiang [République populaire de Chine] ; Wen-Xue Wu [République populaire de Chine]Source :
- Infection and Immunity [ 0019-9567 ] ; 2019.
Abstract
IgA plays an important role in mucosal immunity against infectious pathogens; however, the molecular mechanism of IgA secretion in response to infection remains largely unknown, particularly in
Url:
DOI: 10.1128/IAI.00697-19
PubMed: 31611272
PubMed Central: 6921651
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Toll-Like Receptor 2 (TLR2) and TLR4 Mediate the IgA Immune Response Induced by <named-content content-type="genus-species">Mycoplasma hyopneumoniae</named-content></title><author><name sortKey="Li, Xia" sort="Li, Xia" uniqKey="Li X" first="Xia" last="Li">Xia Li</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing, China</addr-line></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Yun Ke" sort="Zhang, Yun Ke" uniqKey="Zhang Y" first="Yun-Ke" last="Zhang">Yun-Ke Zhang</name><affiliation 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type="wicri:Area/Main/Exploration">000320</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Toll-Like Receptor 2 (TLR2) and TLR4 Mediate the IgA Immune Response Induced by <named-content content-type="genus-species">Mycoplasma hyopneumoniae</named-content></title><author><name sortKey="Li, Xia" sort="Li, Xia" uniqKey="Li X" first="Xia" last="Li">Xia Li</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing, China</addr-line></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Yun Ke" sort="Zhang, Yun Ke" uniqKey="Zhang Y" first="Yun-Ke" last="Zhang">Yun-Ke Zhang</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing, China</addr-line></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yin, Bao" sort="Yin, Bao" uniqKey="Yin B" first="Bao" last="Yin">Bao Yin</name><affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>National Feed Drug Reference Laboratories, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China</addr-line></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Feed Drug Reference Laboratories, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Liang, Jing Bo" sort="Liang, Jing Bo" uniqKey="Liang J" first="Jing-Bo" last="Liang">Jing-Bo Liang</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing, China</addr-line></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Jiang, Fei" sort="Jiang, Fei" uniqKey="Jiang F" first="Fei" last="Jiang">Fei Jiang</name><affiliation wicri:level="3"><nlm:aff id="aff3"><addr-line>China Animal Disease Control Center (CADC), Beijing, China</addr-line></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>China Animal Disease Control Center (CADC), Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wu, Wen Xue" sort="Wu, Wen Xue" uniqKey="Wu W" first="Wen-Xue" last="Wu">Wen-Xue Wu</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing, China</addr-line></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></analytic><series><title level="j">Infection and Immunity</title><idno type="ISSN">0019-9567</idno><idno type="eISSN">1098-5522</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>IgA plays an important role in mucosal immunity against infectious pathogens; however, the molecular mechanism of IgA secretion in response to infection remains largely unknown, particularly in <named-content content-type="genus-species">Mycoplasma</named-content> spp. In this study, we found that the levels of IgA in the peripheral blood serum, bronchoalveolar lavage fluid, nasal mucosa, trachea, hilar lymph nodes, and lung tissues of pigs increased significantly after infection with <named-content content-type="genus-species">Mycoplasma hyopneumoniae</named-content>.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Redondo, 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Castagna</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Li, Xia" sort="Li, Xia" uniqKey="Li X" first="Xia" last="Li">Xia Li</name></noRegion><name sortKey="Jiang, Fei" sort="Jiang, Fei" uniqKey="Jiang F" first="Fei" last="Jiang">Fei Jiang</name><name sortKey="Liang, Jing Bo" sort="Liang, Jing Bo" uniqKey="Liang J" first="Jing-Bo" last="Liang">Jing-Bo Liang</name><name sortKey="Wu, Wen Xue" sort="Wu, Wen Xue" uniqKey="Wu W" first="Wen-Xue" last="Wu">Wen-Xue Wu</name><name sortKey="Yin, Bao" sort="Yin, Bao" uniqKey="Yin B" first="Bao" last="Yin">Bao Yin</name><name sortKey="Zhang, Yun Ke" sort="Zhang, Yun Ke" uniqKey="Zhang Y" first="Yun-Ke" last="Zhang">Yun-Ke Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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